Search results for "Bronchial biopsy"

showing 3 items of 3 documents

Heat shock protein-27 protects human bronchial epithelial cells against oxidative stress-mediated apoptosis: possible implication in asthma.

2002

Inflammation of the human bronchial epithelium, as observed in asthmatics, is characterized by the selective death of the columnar epithelial cells, which desquamate from the basal cells. Tissue repair initiates from basal cells that resist inflammation. Here, we have evaluated the extent of apoptosis as well as the Hsp27 level of expression in epithelial cells from bronchial biopsy samples taken from normal and asthmatic subjects. Hsp27 is a chaperone whose expression protects against oxidative stress. We report that in asthmatic subjects the basal epithelium cells express a high level of Hsp27 but no apoptotic morphology. In contrast, apoptotic columnar cells are devoid of Hsp27 expressio…

Adultendocrine systemanimal structuresHSP27 Heat-Shock ProteinsInflammationApoptosisBronchiColumnar CellRespiratory MucosaBiologymedicine.disease_causeBiochemistryGene Expression Regulation EnzymologicHsp27Heat shock proteinmedicineBronchial BiopsyHumansHeat-Shock ProteinsEpithelial CellsCell BiologyHydrogen PeroxideOriginal ArticlesMiddle AgedOxidantsEpitheliumAsthmaCell biologyNeoplasm ProteinsOxidative Stressmedicine.anatomical_structureApoptosisImmunologybiology.proteinmedicine.symptomOxidative stressMolecular ChaperonesCell stresschaperones
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Técnicas fibrobroncoscópicas especiales: lavado broncoalveolar, biopsia bronquial y biopsia transbronquial

2005

Este artículo completa las recomendaciones sobre el uso y aplicaciones del broncoscopio flexible en la infancia, del Grupo de Técnicas de la Sociedad Española de Neumología Pediátrica, incluyendo los procedimientos que, con fines diagnósticos y ocasionalmente terapéuticos, se aplican con mayor frecuencia durante la práctica de la broncoscopia flexible: el lavado broncoalveolar y las biopsias bronquial y transbronquial. Se realizan también recomendaciones para la práctica del lavado broncoalveolar no broncoscópico.Se revisan las indicaciones, contraindicaciones, recursos materiales, el cuidado y monitorización del paciente previo, durante y posterior al procedimiento, y las complicaciones de…

Bronchoalveolar lavagemedicine.medical_specialtymedicine.diagnostic_testbusiness.industryFlexible bronchoscopyBronchialbiopsyGuidelineGuidelinesPediatricsRJ1-570Bronchoalveolar lavageTransbronchial biopsyPediatrics Perinatology and Child HealthBiopsymedicineBronchial BiopsyRadiologyTransbronchial biopsybusinessChildrenFlexible bronchoscopyPulmonologistsAnales de Pediatría
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Airway inflammation in healthy smokers

2012

Cigarette smoking is a risk factor associated with lung cancer and many other neoplasms of various organs, coronary artery disease and numerous vascular disorders, Chronic Obstructive Pulmonary Disease (COPD) and other types of lung diseases [13]. Much work has been done on the in vitro and ex vivo carcinogenetic effects of tobacco smoking while the effects of smoking on innate and adaptive immune function have been studied to a lesser degree. Recent data suggests that cigarette smoke alters the functions of the immune system and increases susceptibility to viral and bacterial infections [4-6]. In the respiratory system along the last years many studies have depicted the changes induced by …

Pulmonary and Respiratory MedicinePopulationlcsh:MedicineHealthy smokersDiseaseBronchitiTobacco smokeMiceBronchial biopsyAirway inflammation BAL Bronchial biopsy COPD Healthy control Healthy smokersmedicineCOPDAnimalsHumansRisk factoreducationLung cancerBronchitisBALInflammationeducation.field_of_studyCOPDmedicine.diagnostic_testAnimalbusiness.industrySmokinglcsh:Rmedicine.diseaseImmunity Innaterespiratory tract diseasesBronchoalveolar lavageImmunologyBronchitisHealthy controlCardiology and Cardiovascular MedicinebusinessHumanAirway inflammation
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